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Rp-cAMPS sodium
CAS No. 142439-94-9
Rp-cAMPS sodium( —— )
Catalog No. M34873 CAS No. 142439-94-9
Rp-cAMPS sodium is a phosphorothioate analog of cAMP, a protein kinase A inhibitor and a membrane-permeable cAMP antagonist that inhibits cAMP-dependent protein kinases by blocking cAMP-induced conformational transitions, and can be used in the study of cardiovascular diseases.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 454 | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameRp-cAMPS sodium
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NoteResearch use only, not for human use.
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Brief DescriptionRp-cAMPS sodium is a phosphorothioate analog of cAMP, a protein kinase A inhibitor and a membrane-permeable cAMP antagonist that inhibits cAMP-dependent protein kinases by blocking cAMP-induced conformational transitions, and can be used in the study of cardiovascular diseases.
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DescriptionRp-cAMPS sodium salt, a cAMP analog, is a potent, competitive cAMP-induced activation of cAMP-dependent PKA I and II (Kis of 12.5 μM and 4.5 μM, respectively) antagonist. Rp-cAMPS sodium salt is resistant to hydrolysis by phosphodiesterases.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayApoptosis
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TargetPKA
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RecptorPKA | cAMP
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Research Area——
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Indication——
Chemical Information
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CAS Number142439-94-9
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Formula Weight367.25
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Molecular FormulaC10H11N5NaO5PS
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Purity>98% (HPLC)
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SolubilityIn Vitro:?H2O : 250 mg/mL (680.74 mM; Ultrasonic)
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SMILESO[C@H]1[C@@H](O[C@@]2([H])[C@@]1([H])OP([S-])(OC2)=O)N3C4=NC=NC(N)=C4N=C3.[Na+]
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. R J de Wit, et al. Inhibitory action of certain cyclophosphate derivatives of cAMP on cAMP-dependent protein kinases. Eur J Biochem. 1984 Jul 16;142(2):255-60.?
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